Detailed Abstract
[BP Oral Presentation 2]
[BP OP 2-4] De novo cancer incidence after cholecystectomy in Korean population
Junghyun YOON3, Yun Kyung JUNG1, Han Joon KIM1, Boyoung PARK2, Dongho CHOI*1
1Department of Surgery, College of Medicine, Hanyang University, Korea
2Department of Preventive Medicine, College of Medicine, Hanyang University, Korea
3Graduate school of Public Health, Hanyang University, Korea
Introduction : We estimated major cancer incidence rates by age and gender after cholecystectomy based on nationwide database and compared the risk of cancer incidence to general population.
Methods : The subjects of this study, 408,769 aged above 20 years, were extracted from the National Health Insurance cohort from 2008-2016. Cancer incidence rates after cholecystectomy were presented by crude rate, and major cancers were compared for their risk with standardized incidence ratio (SIR).
Results : Compared with the general population, the risk of all cancers in male and female who had cholecystectomy was close to unity. According to the types of cancer, the risk of gastric and lung cancer was lower than the general population, but the incidence of cancer in the colon and liver was high. The most common cancers in male after cholecystectomy were thyroid cancer, gastric cancer and lung cancer by age groups (20-34, 35-64, 65+ years). The SIR of colon cancer (5.8, 2.2 and 1.4) was higher in all age groups. Other higher risk of cancers were thyroid at the age of 20-34 and liver at the age of 35-64. In female, thyroid and colon were the highest incidence rates of cancer in the corresponding all age groups. As with men, the risk of colon cancer (5.7, 1.9 and 1.4) compared to the general population was high in all age groups.
Conclusions : Patients with cholecystectomy are needed a preventive strategy considering cancer, which is more likely to occur than the general population according to gender and age.
Methods : The subjects of this study, 408,769 aged above 20 years, were extracted from the National Health Insurance cohort from 2008-2016. Cancer incidence rates after cholecystectomy were presented by crude rate, and major cancers were compared for their risk with standardized incidence ratio (SIR).
Results : Compared with the general population, the risk of all cancers in male and female who had cholecystectomy was close to unity. According to the types of cancer, the risk of gastric and lung cancer was lower than the general population, but the incidence of cancer in the colon and liver was high. The most common cancers in male after cholecystectomy were thyroid cancer, gastric cancer and lung cancer by age groups (20-34, 35-64, 65+ years). The SIR of colon cancer (5.8, 2.2 and 1.4) was higher in all age groups. Other higher risk of cancers were thyroid at the age of 20-34 and liver at the age of 35-64. In female, thyroid and colon were the highest incidence rates of cancer in the corresponding all age groups. As with men, the risk of colon cancer (5.7, 1.9 and 1.4) compared to the general population was high in all age groups.
Conclusions : Patients with cholecystectomy are needed a preventive strategy considering cancer, which is more likely to occur than the general population according to gender and age.
SESSION
BP Oral Presentation 2
Room B 7/27/2020 2:30 PM - 2:40 PM