Introduction : Recently, early recovery after surgery has become popular trend. In that context, proper nutrition is very important for a quick recovery. The aim of this study was to evaluate the effects of nutritional interventions on the use of Encover®, an oral nutritional supplement, in patients undergoing surgery for hepatobiliary, pancreas disease.

Methods : A prospective case-control study involving patients diagnosed and treated for hepatobiliary, pancreas disease in Gangnam Severance Hospital from 2018-09 to 2019-04. Through randomization, the patients were divided into the experimental group(22 patients) and the control group(27 patients). And the basic anthropometric measurements and PG-SGA nutrition evaluations were performed before surgery and before discharge. After discharge, the experimental group instructed to take 2 packs of Encover® daily for 7 days, but not in the control group. 14 days later, we went out on an outpatient basis for basic anthropometric measurements, PGSGA nutritional assessments, and meal diaries.

Results : The experimental results showed that the change in body weight of the experimental group was -4.27 ± 3.65, -3.82 ± 2.84 in the control group, but it was not significant(P: 0.627). There was also no significant difference in somatic mass, body fat, lean body mass, and muscle mass. Similarly, the follow-up PGSGA score was 9.5 ± 3.96 in the experimental group and 11.3 ± 3.46 in the control group, and no significant results were obtained(P:0.09).

Conclusions : In conclusion, short-term Encover® doses after surgery may not produce significant results in weight gain or other body composition (somatic cell mass, body fat, lean body or muscle mass).