Detailed Abstract
[E-poster]
[EP109] Bactibilia is a frequent event at the time of pancreaticoduodenectomy and it is associated with increased rates of clinically relevant pancreatic fistula
Traian DUMITRASCU*1, Vladislav BRASOVEANU1, Irinel POPESCU1, Cezar STROESCU1, 2, Florin ZAHARIE3, Raluca BODEA3, Mihnea IONESCU1, Cornel IANCU3, Nadim AL HAJJAR3, Catalin VASILESCU1, Octav GINGHINA4, Ionut HUTANU5, Radu ZAMFIR1, Florin GRAUR3, Lucian MOCAN3, Leonard DAVID1, Gabriel MITULESCU1, Narcis COPCA2, Viorel SCRIPCARIU5, Sorin ALEXANDRESCU1
1Department of General Surgery and Liver Transplant, Fundeni Clinical Institute, Bucharest, Rumania
22nd Department of General Surgery and Transplant, St. Mary Hospital, Bucharest, Rumania
33rd Department of Surgery, “Octavian Fodor” Regional Institute of Gastroenterology and Hepatology, Cluj-Napoca, Rumania
4Department of Surgical Oncology, St. John Emergency Hospital, Bucharest, Rumania
51st Department of Surgery, Regional Institute of Oncology, Iassy, Rumania
Introduction : Pancreaticoduodenectomy (PD) is a complex surgical procedure, with widely reported increased morbidity rates. The study aims to explore the impact of positive bile culture at the time of surgery on the early postoperative outcomes after PD.
Methods : All the patients with PD and intraoperative bile culture were selected from the Romanian Pancreatic Resections Study Group database (2016, October 1 – 2019, December 31). The data were prospectively collected and the patients were divided in two groups: with bactibilia (104 patients) and without positive bile culture (126 patients). The postoperative complications were compared between the groups.
Results : Positive bile cultures were observed in 45.2% of the patients. Bactibilia was associated with statistically significant increased rates of grade B-C pancreatic fistula (17.3% vs. 7.9%, p = 0.041). No differences were observed between the group of patients with and without positive bile cultures for the overall and severe morbidity, overall pancreatic fistula, overall and grade B-C delayed gastric emptying, overall and grade B-C postoperative hemorrhage, overall and grade B-C bile leak, wound infections, re-laparotomy for complications and mortality rates (p values ≥ 0.082).
Conclusions : Positive bile cultures are frequent during PD and are associated with increased risk of clinically relevant pancreatic fistula formation. Thus, routine intraoperative bile sampling should be performed during PD.
Methods : All the patients with PD and intraoperative bile culture were selected from the Romanian Pancreatic Resections Study Group database (2016, October 1 – 2019, December 31). The data were prospectively collected and the patients were divided in two groups: with bactibilia (104 patients) and without positive bile culture (126 patients). The postoperative complications were compared between the groups.
Results : Positive bile cultures were observed in 45.2% of the patients. Bactibilia was associated with statistically significant increased rates of grade B-C pancreatic fistula (17.3% vs. 7.9%, p = 0.041). No differences were observed between the group of patients with and without positive bile cultures for the overall and severe morbidity, overall pancreatic fistula, overall and grade B-C delayed gastric emptying, overall and grade B-C postoperative hemorrhage, overall and grade B-C bile leak, wound infections, re-laparotomy for complications and mortality rates (p values ≥ 0.082).
Conclusions : Positive bile cultures are frequent during PD and are associated with increased risk of clinically relevant pancreatic fistula formation. Thus, routine intraoperative bile sampling should be performed during PD.
SESSION
E-poster
E-Session 7/27 ~ 7/29 ALL DAY