Detailed Abstract
[E-poster]
[EP099] Should patient’s age be considered when performing pancreaticoduodenectomy for periampullary cancer?: National database analysis in South Korea
Chang Moo KANG1, 2, Hyeo Seong HWANG1, Jin Ho LEE3, Jung Kyu CHOI4, Ho Kyoung HWANG1, 2, Jae Uk CHUNG3, Woo Jung LEE1, 2, Kuk Hwan KWON*3
1Division of HBP Surgery, Department of Surgery, Yonsei University College of Medicine, Korea
2Pancreatobiliary Cancer Center, Yonsei Cancer Center, Severance Hospital, Korea
3Department of Surgery, National Health Insurance Service Ilsan Hospital, Goyang, Korea
4Department of Policy Research Affairs, National Health Insurance Service Ilsan Hospital, Korea
Introduction : The incidence of periampullary cancer in the elderly is increasing. Safety and oncologic effectiveness of pancreaticoduodenectomy (PD) in elderly patients is still controversial.
Methods : From 2002 to 2016, patients with periampullary cancer were evaluated. Customized health information data provided by the National Health Insurance Corporation (NHIS-2018-1-157) were used for analysis. Chronological changes in the incidence of periampullary cancer and long-term survival outcomes were estimated according to patients’ age.
Results : A total of 148,080 patients were found to have periampullary cancer. Chronologically, the incidence of periampullary cancer increased, and the proportion of elderly patients with periampullary cancer prominently increased (about 2.1 times in patients in their 70s and about 4.7 times in those aged over 80 years). The number of patients with Pylorus preserving pancreaticoduodenectomy(PPPD) in their 70s (about 5.6 times, p<0.001) and over 80 years of age (about 8.9 times, p<0.001) was much higher than the number of patients aged below 50 years (about 1.7 times) and in their 60s (about 2.5 times). Long-term survival was different according to diagnosis (p<0.001). However, it was observed that age was a factor attenuating the survival of patients with resected periampullary cancers (p<0.001).
Conclusions : The incidence of periampullary cancer is increasing in the elderly. Therefore, PD can be considered. However, age was found to attenuate the long-term survival outcome of patients with resected periampullary cancer. The present data can be helpful in the decision-making process for elderly patients with periampullary cancer.
Methods : From 2002 to 2016, patients with periampullary cancer were evaluated. Customized health information data provided by the National Health Insurance Corporation (NHIS-2018-1-157) were used for analysis. Chronological changes in the incidence of periampullary cancer and long-term survival outcomes were estimated according to patients’ age.
Results : A total of 148,080 patients were found to have periampullary cancer. Chronologically, the incidence of periampullary cancer increased, and the proportion of elderly patients with periampullary cancer prominently increased (about 2.1 times in patients in their 70s and about 4.7 times in those aged over 80 years). The number of patients with Pylorus preserving pancreaticoduodenectomy(PPPD) in their 70s (about 5.6 times, p<0.001) and over 80 years of age (about 8.9 times, p<0.001) was much higher than the number of patients aged below 50 years (about 1.7 times) and in their 60s (about 2.5 times). Long-term survival was different according to diagnosis (p<0.001). However, it was observed that age was a factor attenuating the survival of patients with resected periampullary cancers (p<0.001).
Conclusions : The incidence of periampullary cancer is increasing in the elderly. Therefore, PD can be considered. However, age was found to attenuate the long-term survival outcome of patients with resected periampullary cancer. The present data can be helpful in the decision-making process for elderly patients with periampullary cancer.
SESSION
E-poster
E-Session 7/27 ~ 7/29 ALL DAY